Gold Coast, Australia (January 3, 2020): The results of a randomized, placebo-controlled, double-blind clinical  trial of perispinal etanercept were published today, confirming the efficacy and remarkable results of perispinal etanercept in a cohort of stroke survivors with relentless, intractable daily pain after stroke. The individuals were treated an average of about 4 years after stroke and each reported constant daily pain after their stroke that had failed to adequately respond to all previous forms of treatment. They received two doses of perispinal etanercept, each two weeks apart, with the control group receiving two doses of saline administered perispinally. The control group had no change in their daily pain, but the etanercept group had a significant reduction in pain, measured at 30 days, with 30% of the etanercept patients showing near complete pain abatement after the first etanercept treatment. The study concludes: “Perispinal etanercept can provide significant and ongoing benefits for the chronic post-stroke management of pain and greater shoulder flexion by the paretic arm. Effects are rapid and highly significant, supporting direct action on brain function.”

The clinical trial results published on January 3, 2020 in the journal  Expert Opinion on Investigational Drugs. Learn More.

Rapid improvement in speech, aphasia, motor function and chronic post-stroke pain immediately following perispinal etanercept (PSE) treatment by Edward Tobinick M.D. Filmed January 2019 at the Institute of Neurological Recovery in Boca Raton, Florida. https://www.strokebreakthrough.com 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

Improvement in minutes, 6 years after stroke, following perispinal etanercept treatment by Edward Tobinick M.D. on January 3, 2019. Treatment at the Institute of Neurological Recovery in Boca Raton, FL. 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

Rapid neurological improvement 2.5 years after brain injury due to cardiac arrest following perispinal etanercept treatment. Treatment by Edward Tobinick M.D. at the INR in Boca Raton, Florida. Filmed December 6, 2018, 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

Many rapid improvements 18 years after stroke. Treatment by Edward Tobinick M.D. at the INR in Boca Raton, Florida. Filmed November 29, 2018, 4K version, with subtitles. Text, images and video © 2018, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

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Improvement in neurological signs and symptoms of thalamic syndrome (Dejerine-Roussy Syndrome) due to a stroke 20 years previously (in 1998) after treatment at the Institute of Neurological Recovery in Boca Raton in September 2018, by Edward Tobinick, M.D. Text, images and video © 2018, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

Improvement in chronic intractable post-stroke sensory dysfunction in a 24 y.o. Danish woman, 5 years after stroke, within minutes after treatment at the Institute of Neurological Recovery in Boca Raton on September 21, 2018, by Edward Tobinick, M.D. Text, images and video © 2018, INR PLLC, all rights reserved.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

Immediate neurological recovery after treatment at the Institute of Neurological Recovery, September 14, 2018, two years after stroke. Improvements noted in speech, aphasia, apraxia and walking within minutes after treatment at the INR in Boca Raton, Florida.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

Immediate neurological recovery after treatment at the INR Boca Raton, August 13, 2018

Immediate neurological recovery after treatment at the INR Boca Raton, August 13, 2018, two years after a brainstem stroke. Improvements noted in chronic post-stroke pain, visual tracking and gait within minutes after treatment.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use

Rapid Improvement in Walking, Balance, Tone & Cognition 3 Years After Stroke

From Kentucky to the INR in Boca Raton, Florida. Published July 16, 2018.

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Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use