Perispinal Etanercept RCT 2019
Gold Coast, Australia (January 3, 2020): The results of a randomized, placebo-controlled, double-blind clinical trial of perispinal etanercept were published today, confirming the efficacy and remarkable results of perispinal etanercept in a cohort of stroke survivors with relentless, intractable daily pain after stroke. The individuals were treated an average of about 4 years after stroke and each reported constant daily pain after their stroke that had failed to adequately respond to all previous forms of treatment. They received two doses of perispinal etanercept, each two weeks apart, with the control group receiving two doses of saline administered perispinally. The control group had no change in their daily pain, but the etanercept group had a significant reduction in pain, measured at 30 days, with 30% of the etanercept patients showing near complete pain abatement after the first etanercept treatment. The study concludes: “Perispinal etanercept can provide significant and ongoing benefits for the chronic post-stroke management of pain and greater shoulder flexion by the paretic arm. Effects are rapid and highly significant, supporting direct action on brain function.”
The clinical trial results published on January 3, 2020 in the journal Expert Opinion on Investigational Drugs. Learn More.
Family from Columbia. Able to walk unassisted immediately after treatment with perispinal etanercept by Dr. Tobinick. Filmed at the Institute of Neurological Recovery in Boca Raton, Florida, December 4, 2019.
Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Walking unassisted for the first time after a stroke 12 years ago, minutes after treatment by Dr. Tobinick, September 11, 2019, at the Institute of Neurological Recovery in Boca Raton, Florida. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Amazing and life-changing behavioral improvements after a single dose of PSE treatment May 2019 by Dr. Tobinick, 22 years after brain injury. Family from Melbourne, Australia, filmed May 10, 2019. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Life-changing improvement after perispinal etanercept (PSE) treatment by Edward Tobinick MD at the Institute of Neurological Recovery in Boca Raton. PSE treatment (single dose) was administered in December 2018. This video was filmed March 22, 2019, 3 1/2 months after treatment. Wife reports sustained and life-changing neurological improvement after a single dose of PSE. PSE treatment was given 2 1/2 years after brain injury due to prolonged cardiac arrest. strokebreakthrough.com 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Immediate improvement in chronic post-stroke shoulder pain and shoulder subluxation. Treatment at the Institute of Neurological Recovery in Boca Raton on March 8, 2019 by Edward Tobinick, M.D. strokebreakthrough.com 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Rapid neurological improvement within minutes, 17 months after a stroke, after treatment at the INR on February 18, 2019. Treatment by Edward Tobinick, M.D. strokebreakthrough.com 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Sustained improvements after PSE, 11 years after stroke. Treatment by Edward Tobinick M.D., at the INR in Boca Raton, Florida. strokebreakthrough.com 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Rapid improvement in speech, chronic central post-stroke pain, and walking 10 years after stroke after perispinal etanercept treatment. Treatment by Edward Tobinick M.D., February 2019, at the INR in Boca Raton, Florida. strokebreakthrough.com 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use
Immediate improvement after multiple strokes following perispinal etanercept treatment. Treatment by Edward Tobinick M.D. at the INR in Boca Raton, Florida. Filmed January 31, 2019. strokebreakthrough.com 4K version with subtitles. Text, images and video © 2019, INR PLLC, all rights reserved.
Disclaimer: Individual results vary, not all patients respond. Additional doses may be necessary to maintain the clinical response. Treatment is innovative (“off-label”). Terms of Use